Idebenone

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• Idebenone

It is an organic compound, yellow crystal or crystalline powder, odorless.

Extremely insoluble in water, easily soluble in chloroform, methanol or absolute ethanol, easily soluble in ethyl acetate, insoluble in n-hexane. It can activate mitochondrial function, improve brain function metabolism and brain dysfunction, improve the utilization rate of glucose in the brain, and promote ATP generation. It can improve the metabolism of the neurotransmitter 5-hydroxytryptamine in the brain, and has strong antioxidant and free radical scavenging effects.

It is mainly used in clinical treatment of central nervous system degeneration diseases related to oxidative compression, such as Parkinson's disease, Alzheimer's disease, multi-infarct dementia, cerebral anemia and brain failure, and also used in the treatment of Friedreich's ataxia. At the same time, it can also be used in cosmetic formulas. It has the cosmetic efficacy of scavenging free radicals, inhibiting lipid peroxidation, inhibiting inflammation, inhibiting DNA damage, photoprotection, reducing pigmentation and so on.

Appearance and properties: Orange acicular crystal obtained from petroleum ether, melting point 46~50℃. Crystallization was obtained from hexane - ethyl acetate, melting point 52~53℃. It is highly soluble in chloroform, methanol or absolute ethanol, easily soluble in ethyl acetate, soluble in most organic solvents, insoluble in hexane, almost insoluble in water.

melting point：52-55℃

boiling poin：497.3ºC at 760 mmHg

flash(ing) point：170.1ºC

index of refraction：1.502

Stability: stable at normal temperature and pressure

Storage condition: Room temperature